End-stage prostate cancer, even when it has spread to multiple areas, can be effectively treated with a chance of cure thanks to radiotherapy. This involves injecting a radioactive substance into the body, which targets and destroys cancer cells. Many patients see a significant reduction in tumor size after several treatments, and in some cases, the tumors disappear entirely. Lutetium-177 PSMA therapy is available in Germany, and you can use services like Booking Health to find clinics and treatment programs that suit your schedule.
The treatment works by using a radiopharmaceutical agent made up of a ligand and a radionuclide. Lutetium-177, the radionuclide, emits beta radiation to destroy tumors, affecting only the targeted area. Ligands act as couriers, delivering the radioactive Lutetium directly to cancer cells. This method is selective because prostate cancer cells have a specific protein, PSMA, which ligands bind to, ensuring the treatment targets only cancerous tissues. The main side effect is dry mouth, as a small amount of PSMA is present in the kidneys and salivary glands. Doctors mitigate this by administering crystalloid solutions and cooling the salivary glands.
Before starting treatment, patients undergo tests to check PSA levels, kidney function, and tumor locations using PSMA-PET scans. The treatment involves a single intravenous injection, followed by a four-day hospital stay to allow the radioactive substance to leave the body. The process is repeated every 4-8 weeks, as long as it remains effective and without severe side effects, which are rare compared to chemotherapy.
Most patients experience a significant reduction in tumor size after the first injection, and some achieve complete remission after several treatments. While this doesn’t guarantee a permanent cure, many cases have shown no recurrence for years. PSMA therapy offers hope for curing advanced prostate cancer. Booking Health can assist with arranging treatment abroad, helping you find the right center and manage travel logistics.
